Description

2'-Fluoropropiophenone is a high-purity fluorinated aromatic ketone, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic introduction of a fluorine atom, which can significantly alter the metabolic stability, bioavailability, and binding affinity of target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and pesticides, where the fluorine atom enhances biological activity and environmental persistence.
• Material Science Research: Acts as a monomer or modifying agent in the creation of specialty polymers and liquid crystals with unique optical or electronic properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, Grignard reactions, and reductions to construct complex fluorinated molecular architectures.
• Chemical Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	2'-Fluoropropiophenone
CAS No.	21120-36-5
Molecular Formula	C9H9FO
Molecular Weight	152.17 g/mol
Synonyms	1-(2-Fluorophenyl)propan-1-one; 2-Fluoropropiophenone; o-Fluoropropiophenone; Propiophenone, 2'-fluoro-; 2-Fluorophenyl ethyl ketone; 2-Fluoro-1-phenyl-1-propanone; 2'-Fluoropropiophenon; 2-Fluoropropiophenon
EINECS	Contact for details

Quality Control

Our 2'-Fluoropropiophenone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry guidelines for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and potential contamination.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.