Description

1H-Imidazole-1-Sulfonic Acid is a versatile and reactive sulfonic acid derivative of imidazole, serving as a key building block and reagent in advanced organic synthesis. Its primary value lies in its ability to act as a sulfonating agent or a protected intermediate for introducing functional groups into complex molecules. This high-purity chemical is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Critical for the synthesis of active pharmaceutical ingredients (APIs), particularly in constructing heterocyclic cores and introducing sulfonate functionalities.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides that require specific sulfonated heterocyclic structures.
• Polymer Chemistry: Acts as a monomer or modifying agent for creating specialty polymers with enhanced properties like solubility or thermal stability.
• Ligand and Catalyst Preparation: Employed in the design and synthesis of novel ligands and organocatalysts for asymmetric synthesis and metal complexation.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic pathways and molecular architectures.
• Dye and Pigment Manufacturing: Utilized in the synthesis of specialized dyes and colorants where the imidazole-sulfonate group imparts specific chromatic or binding properties.

Basic Information

Product Name	1H-Imidazole-1-Sulfonic Acid
CAS No.	21108-81-6
Molecular Formula	C3H4N2O3S
Molecular Weight	148.14 g/mol
Synonyms	Imidazole-1-sulfonic acid; 1-Imidazolesulfonic Acid; Imidazol-1-ylsulfonic Acid; 1H-Imidazole-1-sulfonic Acid; 1-Sulfoimidazole; Imidazole Sulfonic Acid; 1-Imidazolesulphonic Acid; 1H-Imidazol-1-ol, 1-oxo-, sulfate (1:1)
EINECS	Contact for details

Quality Control

Our 1H-Imidazole-1-Sulfonic Acid is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing to ensure high purity and consistency, meeting the stringent requirements for synthetic intermediates. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key parameters such as assay, identity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.