Description

3,4'-Bis(Trifluoromethyl)Benzophenone is a high-value fluorinated aromatic ketone building block. This compound matters for its role as a critical intermediate in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where the introduction of trifluoromethyl groups is essential for modulating electronic properties, lipophilicity, and metabolic stability. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty polymer industries.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitors and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides where the CF3 group enhances biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a core building block for fluorinated liquid crystals and organic light-emitting diode (OLED) materials, improving charge transport and stability.
• Polymer Modification: Incorporated into specialty polymers to enhance thermal stability, chemical resistance, and optical properties.
• Advanced Ligand Synthesis: Utilized in the preparation of fluorinated ligands for catalysis and metal-organic frameworks (MOFs).
• Organic Synthesis Research: A versatile reagent for introducing bis(trifluoromethyl)phenyl motifs in complex molecule construction via cross-coupling and other reactions.

Basic Information

Product Name	3,4'-Bis(Trifluoromethyl)Benzophenone
CAS No.	21084-22-0
Molecular Formula	C15H8F6O
Molecular Weight	318.22 g/mol
Synonyms	3,4'-Di(trifluoromethyl)benzophenone; [3-(Trifluoromethyl)phenyl][4-(trifluoromethyl)phenyl]methanone; 3,4'-Bis(trifluoromethyl)benzophenone; 3,4'-Di(trifluoromethyl)benzophenone; 3-(Trifluoromethyl)-4'-(trifluoromethyl)benzophenone; α,α,α,α',α',α'-Hexafluoro-3,4'-dimethylbenzophenone
EINECS	Contact for details

Quality Control

Our 3,4'-Bis(Trifluoromethyl)Benzophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee batch-to-batch consistency and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.