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(3R,10R)-1,2,3β,4,4Aβ,5β,6,7,8,8Aβ-Decahydro-1,7β-Dimethyl-3,5-Ethanoquinolin-10-Ol CAS NO 21041-43-0
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CAS No.:21041-43-0
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
(3R,10R)-1,2,3β,4,4Aβ,5β,6,7,8,8Aβ-Decahydro-1,7β-Dimethyl-3,5-Ethanoquinolin-10-Ol is a high-purity, stereochemically defined alkaloid derivative with a complex polycyclic structure. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, valued for its rigid molecular framework. It is primarily utilized by research institutions and pharmaceutical development companies engaged in the synthesis of novel active pharmaceutical ingredients (APIs), natural product analogs, and specialized fine chemicals.
Application
- Pharmaceutical Intermediate: A key chiral synthon for the research and development of new therapeutic agents, particularly in alkaloid-based drug discovery.
- Asymmetric Synthesis: Employed as a sophisticated starting material or ligand precursor in catalytic asymmetric reactions to induce stereoselectivity.
- Natural Product Synthesis: Used in the total or semi-synthesis of complex natural products with quinolizidine or related structural motifs.
- Chemical Research: Serves as a reference standard or model compound in methodological studies and structural chemistry investigations.
- Fine Chemical Production: Incorporated into the manufacturing of high-value, specialty chemicals for advanced material science applications.
Basic Information
| Product Name | (3R,10R)-1,2,3β,4,4Aβ,5β,6,7,8,8Aβ-Decahydro-1,7β-Dimethyl-3,5-Ethanoquinolin-10-Ol |
| CAS No. | 21041-43-0 |
| Molecular Formula | C15H25NO |
| Molecular Weight | 235.37 g/mol |
| Synonyms | 10-Hydroxy-1,7β-dimethyl-3,5-ethanoquinolizidine; (3R,10R)-Decahydro-1,7β-dimethyl-3,5-ethanoquinolin-10-ol; 3,5-ethanoquinolizidine-10-ol derivative; 1,7β-Dimethyl-3,5-ethano-10-hydroxyquinolizidine; (3R,10R)-1,7β-Dimethyl-3,5-ethanoquinolizidin-10-ol; Quinolizidine alkaloid intermediate; Stereoisomer of lupin alkaloid core |
| EINECS | Contact for details |
Quality Control
Our (3R,10R)-1,2,3β,4,4Aβ,5β,6,7,8,8Aβ-Decahydro-1,7β-Dimethyl-3,5-Ethanoquinolin-10-Ol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the exacting standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC), and specific rotation is provided with each shipment.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound should be handled under inert atmosphere if prolonged storage is anticipated to prevent potential degradation.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 98.0% |
| Chiral Purity (Chiral HPLC) | ≥ 99.0% ee |
| Specific Rotation [α]20/D | Contact for details |
| Loss on Drying | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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