Description

Ethyl 5-Bromonicotinate is a high-purity brominated nicotinate ester, a key building block in advanced organic synthesis. This compound is valued for its versatility as a reactive intermediate, enabling the construction of complex heterocyclic scaffolds. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the nicotinate core.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials, such as organic light-emitting diodes (OLEDs) and conductive polymers.
• Chemical Biology Probes: Utilized to synthesize molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom synthesis projects and scale-up manufacturing under cGMP conditions.

Basic Information

Product Name	Ethyl 5-Bromonicotinate
CAS No.	20986-40-7
Molecular Formula	C8H8BrNO2
Molecular Weight	230.06 g/mol
Synonyms	5-Bromonicotinic Acid Ethyl Ester; Ethyl 5-Bromo-3-pyridinecarboxylate; 3-Pyridinecarboxylic acid, 5-bromo-, ethyl ester; 5-Bromo-3-pyridinecarboxylic acid ethyl ester; 5-Bromopyridine-3-carboxylic acid ethyl ester; 20986-40-7; Ethyl 5-bromopyridine-3-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 5-Bromonicotinate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications from research to commercial-scale cGMP synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.