Description

6-Acrylamidohexanoic Acid is a bifunctional monomer featuring both a polymerizable acrylamide group and a terminal carboxylic acid, making it a versatile building block for advanced material synthesis. This compound is crucial for creating custom polymers with tailored properties such as specific reactivity, hydrophilicity, or adhesion. It is primarily sought by R&D chemists and process engineers in the pharmaceutical intermediates, specialty adhesives, hydrogel development, and surface coating sectors for introducing functional handles into polymeric architectures.

Application

• Pharmaceutical Intermediates: Serves as a key synthon for constructing drug conjugates or prodrugs, leveraging its carboxylic acid group for further derivatization.
• Hydrogel Synthesis: Used as a co-monomer to introduce ionic character and pH-responsive swelling behavior into cross-linked polymer networks for biomedical and agricultural applications.
• Specialty Adhesives & Coatings: Incorporated into acrylic copolymer formulations to enhance adhesion to difficult substrates and improve coating durability through cross-linking.
• Surface Modification: Employed to graft functional polymer brushes onto surfaces (e.g., silica, metals) for creating biocompatible or anti-fouling interfaces.
• Chromatography Media: Acts as a spacer or functional ligand in the synthesis of affinity chromatography resins for protein purification.
• Dental Materials: Utilized in the development of restorative resins and adhesives to improve mechanical strength and bonding to tooth structure.
• Contact Lens Materials: A potential component in the formulation of hydrophilic, oxygen-permeable silicone hydrogel materials.
• Research & Development: A valuable tool for academic and industrial researchers exploring novel functional polymers and macromolecular architectures.

Basic Information

Product Name	6-Acrylamidohexanoic Acid
CAS No.	20766-85-2
Molecular Formula	C9H15NO3
Molecular Weight	185.22 g/mol
Synonyms	6-Acrylamidocaproic Acid; N-Acryloyl-6-aminocaproic Acid; Acrylamidocaproic Acid; N-(5-Carboxypentyl)acrylamide; 6-(Acrylamido)hexanoic Acid; N-Acryloyl-ε-aminocaproic Acid; AAH; ACA
EINECS	244-045-8

Quality Control

Our 6-Acrylamidohexanoic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from HPLC, NMR, and other relevant techniques. Our quality commitment ensures the material meets the stringent requirements for research and industrial synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent absorption of atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	95 - 100 °C
Loss on Drying	≤ 1.0 %
Heavy Metals (as Pb)	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.