Description

2-Methyl-5-Phenyl-2H-Tetrazole is a versatile heterocyclic compound belonging to the tetrazole family, characterized by a five-membered ring containing four nitrogen atoms. This compound serves as a valuable pharmacophore and synthetic intermediate in advanced organic synthesis, particularly for the development of active pharmaceutical ingredients (APIs) and functional materials. It is primarily utilized by pharmaceutical R&D, agrochemical manufacturers, and material science researchers seeking to incorporate the tetrazole moiety for its metabolic stability and bioisosteric properties.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of sartans (e.g., Valsartan analogs) and other drug candidates where the tetrazole ring acts as a carboxylic acid bioisostere.
• Agrochemical Synthesis: Used in the research and production of modern herbicides and pesticides, contributing to improved efficacy and environmental profile.
• Material Science: Serves as a precursor for energetic materials, coordination polymers, and ligands in catalysis due to its high nitrogen content and coordination ability.
• Chemical Research: Employed in academic and industrial laboratories for studying 1,3-dipolar cycloaddition reactions and developing novel heterocyclic compounds.
• Coordination Chemistry: Acts as a versatile ligand for forming metal-organic frameworks (MOFs) and complexes with transition metals.

Basic Information

Product Name	2-Methyl-5-Phenyl-2H-Tetrazole
CAS No.	20743-49-1
Molecular Formula	C8H8N4
Molecular Weight	160.18 g/mol
Synonyms	5-Phenyl-2-methyl-2H-tetrazole; 2-Methyl-5-phenyltetrazole; 2H-Tetrazole, 2-methyl-5-phenyl-; 2-Methyl-5-phenyl-1,2,3,4-tetrazole; 5-Phenyl-2-methyltetrazole; NSC 406913; 2-Methyl-5-phenyl-v-tetrazole
EINECS	Contact for details

Quality Control

Our production of 2-Methyl-5-Phenyl-2H-Tetrazole adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure consistent high quality and batch-to-batch reproducibility. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical parameters. Our quality system is designed to support cGMP and ISO standards for traceability and documentation, making our product suitable for regulated research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	118 - 122 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.