Description

3-O,4-O,6-o-Tribenzyl-D-Mannopyranose is a key protected carbohydrate intermediate, specifically a fully benzylated derivative of D-mannose. This compound is essential for synthetic chemists as it provides a versatile scaffold for the selective manipulation of sugar hydroxyl groups in complex organic synthesis. It is primarily used in the research and development of pharmaceuticals, novel glycoconjugates, and sophisticated chiral building blocks for advanced materials.

Application

• Pharmaceutical Intermediate: Critical starting material for the synthesis of nucleoside analogs, antiviral agents, and other bioactive molecules where the mannose scaffold is required.
• Glycochemistry Research: Serves as a protected precursor for the controlled synthesis of oligosaccharides, glycopeptides, and glycomimetics in academic and industrial R&D.
• Chiral Pool Synthesis: Utilized as a source of chirality for constructing complex natural products and asymmetric catalysts.
• Chemical Biology Probes: Used in the development of labeled sugars and metabolic probes for studying glycosylation pathways and carbohydrate-protein interactions.
• Process Development: Employed in scale-up and route optimization for the production of carbohydrate-based Active Pharmaceutical Ingredients (APIs).

Basic Information

Product Name	3-O,4-O,6-o-Tribenzyl-D-Mannopyranose
CAS No.	20672-66-6
Molecular Formula	C27H30O6
Molecular Weight	450.52 g/mol
Synonyms	1,2-O-Isopropylidene-3,4,6-tri-O-benzyl-α-D-mannofuranose; 3,4,6-Tri-O-benzyl-1,2-O-isopropylidene-α-D-mannofuranose; Tribenzyl Isopropylidene Mannose; D-Mannose, 3,4,6-tris-O-(phenylmethyl)-, 1,2-O-(1-methylethylidene)-, (α-D)-; 1,2:5,6-Di-O-isopropylidene-α-D-mannofuranose tribenzyl ether (common misnomer); α-D-Mannofuranose, 3,4,6-tris-O-(phenylmethyl)-, 1,2-O-(1-methylethylidene)-
EINECS	Contact for details

Quality Control

Our 3-O,4-O,6-o-Tribenzyl-D-Mannopyranose is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and chiral analysis to ensure stereochemical integrity. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.