Description

(S)-Cyclohexyl-Hydroxy-Phenyl-Acetic Acid is a high-purity chiral intermediate of significant importance in the synthesis of enantiomerically pure pharmaceuticals. Its value lies in its role as a key building block for active pharmaceutical ingredients (APIs), particularly in the development of drugs requiring specific stereochemistry for optimal efficacy and safety. This compound is essential for R&D laboratories and production facilities in the pharmaceutical and fine chemical industries focused on creating novel therapeutics.

Application

• Pharmaceutical Intermediate: A critical chiral building block in the synthesis of enantiomerically pure Active Pharmaceutical Ingredients (APIs).
• Asymmetric Synthesis: Used as a starting material or resolving agent in stereoselective chemical reactions.
• Research & Development: Serves as a standard or reagent in medicinal chemistry programs for drug discovery.
• Fine Chemical Production: Employed in the manufacture of advanced, high-value specialty chemicals.
• Agrochemical Synthesis: Potential intermediate in the development of chiral pesticides or herbicides.

Basic Information

Product Name	(S)-Cyclohexyl-Hydroxy-Phenyl-Acetic Acid
CAS No.	20585-34-6
Molecular Formula	C₁₄H₁₈O₃
Molecular Weight	234.29 g/mol
Synonyms	(S)-2-Hydroxy-2-cyclohexyl-2-phenylacetic acid; (S)-α-Cyclohexylmandelic acid; (S)-Cyclohexyl(phenyl)glycolic acid; (S)-HMPA; (S)-2-Cyclohexyl-2-hydroxy-2-phenylacetic acid; (S)-2-Phenyl-2-cyclohexyl-2-hydroxyacetic acid; L-Cyclohexylmandelic acid
EINECS	Contact for details

Quality Control

Our (S)-Cyclohexyl-Hydroxy-Phenyl-Acetic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical intermediate applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents. Due to its acidic nature, handle with appropriate engineering controls.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.