Description

2-Chloro-5-(Trifluoromethyl)Benzamide is a high-purity, halogenated benzamide derivative serving as a critical building block in advanced organic synthesis. Its value lies in the unique reactivity imparted by the trifluoromethyl and chloro substituents, enabling the construction of complex molecules with tailored properties. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system and metabolic disorders.
• Agrochemical Synthesis: Building block for developing next-generation herbicides, fungicides, and plant growth regulators with enhanced efficacy and environmental profiles.
• Material Science Research: Used in creating specialty polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing groups.
• Chemical Biology & Proteomics: Serves as a versatile scaffold for designing molecular probes and enzyme inhibitors in drug discovery programs.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and development of scalable synthetic routes.

Basic Information

Product Name	2-Chloro-5-(Trifluoromethyl)Benzamide
CAS No.	20566-93-2
Molecular Formula	C8H5ClF3NO
Molecular Weight	223.58 g/mol
Synonyms	2-Chloro-α,α,α-trifluoro-m-toluamide; 2-Chloro-α,α,α-trifluoro-3-methylbenzamide; 2-Chloro-3-(trifluoromethyl)benzamide; 2-Chloro-5-(trifluoromethyl)benzoic acid amide; 2-Chloro-5-trifluoromethylbenzamide; Benzamide, 2-chloro-5-(trifluoromethyl)-; m-(Trifluoromethyl)-2-chlorobenzamide
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-5-(Trifluoromethyl)Benzamide is manufactured under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency meet the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	142 - 147 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.