Description

Methyl Pentafluorobut-3-Enoate is a high-value fluorinated building block and specialty intermediate. This compound is prized for its unique reactivity profile, enabling the efficient introduction of a pentafluorobut-3-enoyl moiety into target molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and advanced materials sectors for synthesizing novel compounds with tailored properties.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates, particularly those requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where fluorine atoms can improve efficacy and environmental profile.
• Material Science: Serves as a monomer or precursor for creating specialty polymers and coatings with unique surface properties, such as oil and water repellency (oleophobicity/hydrophobicity).
• Liquid Crystal & Electronic Materials: Employed in the synthesis of fluorinated components for liquid crystal displays (LCDs) and organic electronic materials.
• Cross-coupling Reactions: Acts as an effective substrate in various palladium-catalyzed cross-coupling reactions to construct complex fluorinated architectures.
• Fluorine Chemistry Research: An essential reagent in academic and industrial laboratories focused on exploring new methodologies in organofluorine chemistry.

Basic Information

Product Name	Methyl Pentafluorobut-3-Enoate
CAS No.	20562-79-2
Molecular Formula	C6H3F5O2
Molecular Weight	202.08 g/mol
Synonyms	Methyl 4,4,5,5,5-pentafluoropent-2-enoate; 4,4,5,5,5-Pentafluoro-3-butenoic Acid Methyl Ester; Methyl Perfluorocrotonate; 2-Butenoic acid, 4,4,5,5,5-pentafluoro-, methyl ester; Methyl Pentafluorocrotonate; Pentafluorocrotonic Acid Methyl Ester; MFCD00042291
EINECS	Contact for details

Quality Control

Our Methyl Pentafluorobut-3-Enoate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place at room temperature (15-25°C). Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use. Keep away from strong bases and fluorides.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.