Description

1-(4-Bromophenyl)But-1-En-3-One is a versatile brominated aromatic ketone building block of significant importance in advanced organic synthesis. Its core value lies in its reactive α,β-unsaturated carbonyl system and the bromine substituent, which serves as a handle for further functionalization via cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to construct complex molecular scaffolds for active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its aromatic structure for bioactive molecule design.
• Material Science Research: Serves as a monomer or building block for creating specialized polymers and organic electronic materials.
• Cross-Coupling Reactions: The bromophenyl group is pivotal in Suzuki, Heck, and other palladium-catalyzed coupling reactions to form biaryl structures.
• Chemical Research & Development: Employed in academic and industrial R&D labs for method development and exploring new reaction pathways in synthetic organic chemistry.
• Ligand and Catalyst Preparation: Useful for synthesizing complex ligands for metal catalysts used in asymmetric synthesis.

Basic Information

Product Name	1-(4-Bromophenyl)But-1-En-3-One
CAS No.	20511-04-0
Molecular Formula	C10H9BrO
Molecular Weight	225.08 g/mol
Synonyms	4'-Bromochalcone; (E)-1-(4-Bromophenyl)-3-buten-1-one; 3-Buten-1-one, 1-(4-bromophenyl)-; 4-Bromobenzylideneacetone; p-Bromochalcone; 1-(p-Bromophenyl)-3-buten-1-one; (E)-4'-Bromochalcone; 4-Bromophenyl vinyl ketone
EINECS	Contact for details

Quality Control

Our 1-(4-Bromophenyl)But-1-En-3-One is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and commercial synthesis. We employ advanced analytical techniques including HPLC, GC, and NMR to verify identity and purity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	78°C - 82°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.