Description

Piperazine, 1-[(Trimethylsilyl)Methyl]- (8Ci,9Ci) is a specialized organosilicon derivative of piperazine, characterized by the presence of a trimethylsilylmethyl group. This functionalization imparts unique steric and electronic properties, making it a valuable building block in advanced organic synthesis and pharmaceutical research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active compounds and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, particularly in central nervous system (CNS) and anti-infective research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its modified piperazine scaffold.
• Ligand and Catalyst Preparation: Serves as a precursor for nitrogen-containing ligands used in transition metal catalysis.
• Organic Synthesis Reagent: Employed in nucleophilic substitution and protection/deprotection strategies due to the reactive silyl group.
• Material Science Research: Investigated for incorporation into polymers and silicon-based hybrid materials to modify physical properties.
• Chemical Biology Probes: Utilized in the design of molecular probes for studying biological systems.

Basic Information

Product Name	Piperazine, 1-[(Trimethylsilyl)Methyl]- (8Ci,9Ci)
CAS No.	20493-91-8
Molecular Formula	C9H22N2Si
Molecular Weight	186.37 g/mol
Synonyms	1-(Trimethylsilylmethyl)piperazine; N-[(Trimethylsilyl)methyl]piperazine; (Trimethylsilylmethyl)piperazine; Piperazine, 1-[(trimethylsilyl)methyl]-; 1-(Trimethylsilyl)methylpiperazine; 1-Piperazine(trimethylsilyl)methane; N-(Trimethylsilylmethyl)piperazine
EINECS	Contact for details

Quality Control

Our Piperazine, 1-[(Trimethylsilyl)Methyl]- is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chromatographic purity analysis and identity confirmation, to ensure consistency and reliability for your critical research and development processes. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect product stability and performance.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.