Description

2,2-Diethoxyacetic Acid is a versatile organic acid ester derivative, primarily valued as a key synthetic intermediate and protecting group reagent in complex organic synthesis. Its unique acetal-protected carboxylic acid structure makes it a crucial building block for constructing sensitive molecules where controlled reactivity is required. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries developing active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring protected carboxyl groups.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators where its diethoxy moiety offers specific reactivity.
• Fine Chemical Building Block: Employed in the manufacture of flavors, fragrances, and specialty polymers that require controlled introduction of acetic acid derivatives.
• Peptide and Organic Synthesis: Acts as a protecting group reagent for carboxylic acids, allowing selective reactions at other sites within a complex molecule.
• Chemical Research & Development: Utilized in academic and industrial R&D labs for methodological development and the synthesis of novel organic compounds.
• Coordination Chemistry: Can function as a ligand or precursor for ligands in metal-organic frameworks (MOFs) and catalytic complexes.

Basic Information

Product Name	2,2-Diethoxyacetic Acid
CAS No.	20461-86-3
Molecular Formula	C6H12O4
Molecular Weight	148.16 g/mol
Synonyms	Acetic acid, 2,2-diethoxy-; Diethoxyacetic acid; (Diethoxymethoxy)formic acid; 2,2-Diethoxyethanoic acid; Glyoxylic acid diethyl acetal; NSC 66487; Glyoxylic acid, diethyl acetal; α,α-Diethoxyacetic acid
EINECS	243-844-9

Quality Control

Our 2,2-Diethoxyacetic Acid is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chromatography and spectroscopy, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for manufacturing, ensuring reliability for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.415 - 1.425
Density (20°C)	1.08 - 1.12 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.