Description

1,2,4,6-Tetra-o-Acetyl-3-Deoxy-3-Fluoro-α-D-Glucopyranose is a key fluorinated carbohydrate derivative, serving as a crucial advanced intermediate in synthetic organic chemistry. Its value lies in providing a protected, reactive scaffold for the precise introduction of fluorine into complex sugar-based molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel nucleoside analogs, enzyme inhibitors, and other bioactive compounds where fluorine substitution is desired to modulate properties like metabolic stability and binding affinity.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of fluorinated nucleoside analogs used as antiviral or anticancer agents.
• Glycobiology Research: Used to prepare fluorinated sugar probes for studying enzyme mechanisms, metabolic pathways, and glycosylation processes.
• Agrochemical Synthesis: Intermediate in the development of novel fluorinated pesticides and herbicides with enhanced activity and environmental profile.
• Diagnostic Agent Development: Potential precursor for fluorinated contrast agents or radiotracers used in medical imaging (e.g., PET scans).
• Material Science: Starting material for synthesizing fluorinated surfactants, polymers, or specialty materials with unique surface properties.
• Chemical Biology Tool: Enables the site-specific incorporation of fluorine into carbohydrates to create mechanistic probes and inhibitors.

Basic Information

Item	Details
Product Name	1,2,4,6-Tetra-o-Acetyl-3-Deoxy-3-Fluoro-α-D-Glucopyranose
CAS No.	20409-32-9
Molecular Formula	C₁₄H₁₉FO₉
Molecular Weight	350.29 g/mol
Synonyms	3-Deoxy-3-fluoro-1,2,4,6-tetra-O-acetyl-α-D-glucopyranose; 1,2,4,6-Tetra-O-acetyl-3-deoxy-3-fluoro-α-D-glucopyranose; 3-Fluoro-1,2,4,6-tetra-O-acetyl-3-deoxy-α-D-glucopyranose; 3-Deoxy-3-fluoro-α-D-glucopyranose tetraacetate; Tetra-O-acetyl-3-deoxy-3-fluoro-α-D-glucose; 20409-32-9; α-D-Glucopyranose, 3-deoxy-3-fluoro-, 1,2,4,6-tetraacetate
EINECS	Contact for details

Quality Control

Our 1,2,4,6-Tetra-o-Acetyl-3-Deoxy-3-Fluoro-α-D-Glucopyranose is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with every shipment. We support development and cGMP manufacturing needs with consistent quality and full traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.