Description

(E)-1-Chloro-1-Buten-3-Yne is a highly reactive halogenated alkyne building block, valued for its unique conjugated system of a chlorine atom, a double bond, and a terminal triple bond. This structure makes it a versatile and critical intermediate for synthesizing complex molecules in advanced chemical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel heterocycles, polymers, and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of potential active pharmaceutical ingredients (APIs), especially for creating complex molecular architectures.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its reactive sites for structural diversification.
• Specialty Polymer & Material Science: Acts as a monomer or cross-linking agent in the development of advanced polymers with specific optical, electronic, or mechanical properties.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for Diels-Alder reactions, cycloadditions, and palladium-catalyzed cross-coupling reactions (e.g., Sonogashira).
• Ligand & Catalyst Development: Useful for preparing novel ligands for metal complexes used in homogeneous catalysis.
• Chemical Research: Fundamental studies on reactivity and mechanism due to its distinct electrophilic and nucleophilic character.

Basic Information

Product Name	(E)-1-Chloro-1-Buten-3-Yne
CAS No.	20374-91-8
Molecular Formula	C4H3Cl
Molecular Weight	86.52 g/mol
Synonyms	trans-1-Chloro-1-buten-3-yne; 1-Chloro-1-buten-3-yne; 1-Chlorobut-1-en-3-yne; (E)-1-Chloro-1-buten-3-yne; 1-Chloro-1-butyne-3-ene; Chlorovinylacetylene; 1-Chlorovinylacetylene; 3-Buten-1-ynyl chloride
EINECS	243-785-5

Quality Control

Every batch of (E)-1-Chloro-1-Buten-3-Yne is produced and analyzed under strict quality protocols to ensure consistency and reliability for your synthetic workflows. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as purity (by GC), identity confirmation, and impurity profiles. Our quality system is designed to support research and development needs where material integrity is paramount.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place, away from incompatible materials such as strong bases and oxidizing agents. Due to its reactivity and nature as a strong acid/organic solvent, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 95.0% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.