Description

Dimethyl 5-Chloroisophthalate is a high-purity organic ester compound, serving as a critical building block in advanced chemical synthesis. Its value lies in providing a reactive aromatic core with a chlorine substituent and two methyl ester groups, enabling precise functionalization for complex molecules. This intermediate is essential for manufacturers in the pharmaceutical, agrochemical, and specialty polymer industries seeking to develop new active ingredients and high-performance materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds with isophthalic acid-derived structures.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the chlorinated aromatic moiety is required for bioactivity.
• Liquid Crystal & Polymer Chemistry: Serves as a monomer or intermediate for creating specialty polymers, liquid crystal displays (LCDs), and high-temperature-resistant engineering plastics.
• Organic Light-Emitting Diodes (OLEDs): Acts as a building block for electron-transport materials and emissive layer components in OLED device manufacturing.
• Dye & Pigment Manufacturing: Utilized in the synthesis of complex organic dyes and pigments, contributing to color fastness and specific spectral properties.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) due to the reactive chlorine atom, facilitating carbon-carbon bond formation.

Basic Information

Product Name	Dimethyl 5-Chloroisophthalate
CAS No.	20330-90-9
Molecular Formula	C10H9ClO4
Molecular Weight	228.63 g/mol
Synonyms	5-Chloroisophthalic Acid Dimethyl Ester; Dimethyl 5-Chloro-1,3-benzenedicarboxylate; 1,3-Benzenedicarboxylic acid, 5-chloro-, dimethyl ester; 5-Chloro-1,3-benzenedicarboxylic acid dimethyl ester; Methyl 5-chloroisophthalate; 5-Chloroisophthalic acid, dimethyl ester; 5-Chlorobenzene-1,3-dicarboxylic acid dimethyl ester
EINECS	243-746-6

Quality Control

Our Dimethyl 5-Chloroisophthalate is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our production adheres to cGMP principles where applicable, ensuring reliability for sensitive applications in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container must be kept tightly closed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.