Description

Niddamycin CAS NO 20283-69-6 is a 16-membered macrolide antibiotic belonging to the leucomycin family, valued for its potent antibacterial activity against Gram-positive bacteria and certain mycoplasmas. Its significance lies in its role as a key intermediate and reference standard in pharmaceutical research and development, particularly for novel antibiotic synthesis. This product is essential for manufacturers and R&D laboratories in the pharmaceutical, veterinary medicine, and agrochemical sectors seeking high-purity bioactive compounds.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of advanced macrolide antibiotics and derivatives.
• Veterinary Medicine: Used in research for developing treatments against bacterial infections in livestock and companion animals.
• Microbiological Research: Employed as a reference standard in antimicrobial susceptibility testing and mechanism-of-action studies.
• Biochemical Studies: Utilized to investigate protein synthesis inhibition and bacterial ribosome function.
• Agrochemical Research: Explored for potential applications in managing bacterial plant pathogens.
• Quality Control: Acts as a certified reference material (CRM) for assay calibration and impurity profiling in antibiotic production.

Basic Information

Product Name	Niddamycin
CAS No.	20283-69-6
Molecular Formula	C42H69NO15
Molecular Weight	828.00 g/mol
Synonyms	Niddamycin; Antibiotic SF-837 A3; Leucomycin A6; 9-Dihydro-16-propionylleucomycin A6; (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-4-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-14-ethyl-12,13-dihydroxy-7-{[(2R,3S,4S,6S)-3-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}-3,5,7,9,11,13-hexamethyl-6-{[(2S,3R,4S,6R)-3-methoxy-4,6-dimethyloxan-2-yl]oxy}oxacyclotetradecane-2,10-dione
EINECS	Contact for details

Quality Control

Our Niddamycin is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets high-grade standards suitable for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, related substances, and residual solvents is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.