Description

3,3-Diphenyl-3H-Diazirine is a specialized heterocyclic organic compound belonging to the diazirine class, known for its unique photoreactive properties. This compound serves as a highly effective photoaffinity labeling agent, enabling the study of biomolecular interactions and binding sites. It is a critical reagent for researchers and manufacturers in the fields of pharmaceutical development, chemical biology, and advanced materials science, where precise molecular tagging is required.

Application

• Photoaffinity Labeling (PAL): A premier reagent for covalent cross-linking of proteins, nucleic acids, and other biomolecules upon UV light activation to map interaction sites.
• Proteomics & Chemical Biology Research: Used in the development of probes for target identification, drug discovery, and understanding metabolic pathways.
• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates and bioactive molecules.
• Surface Modification & Polymer Chemistry: Employed to introduce photoreactive groups onto polymers, nanoparticles, and surfaces for functional material creation.
• Bioconjugation: Facilitates the stable attachment of ligands, dyes, or other molecules to biological entities for diagnostic and therapeutic applications.

Basic Information

Product Name	3,3-Diphenyl-3H-Diazirine
CAS No.	20188-03-8
Molecular Formula	C14H10N2
Molecular Weight	206.24 g/mol
Synonyms	3,3-Diphenyldiazirine; Diphenyldiazirine; 3H-Diazirine, 3,3-diphenyl-; 3,3-Diphenyl-3H-diazirine; Diazirine, 3,3-diphenyl-; 3,3-Diphenyl-diaziridin; Diphenylcarbene precursor
EINECS	Contact for details

Quality Control

Our 3,3-Diphenyl-3H-Diazirine is produced under stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and thermal degradation. Keep the container in a cool, dry, and well-ventilated place away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	48 - 52 °C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.