Description

2,3-Dihydro-2-Hydroxy-1H-Isophosphindoline 2-Oxide is a specialized organophosphorus compound of significant interest in advanced chemical synthesis. This heterocyclic phosphinate serves as a versatile and valuable building block for the development of novel materials and active pharmaceutical ingredients. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for its unique reactivity and structural properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting neurological and metabolic pathways.
• Ligand Synthesis: Used in the preparation of chiral and achiral ligands for catalysis and metal complexation.
• Agrochemical Research: Serves as a building block for developing new herbicides, insecticides, and plant growth regulators with improved efficacy.
• Material Science: Incorporated into polymers and advanced materials to impart flame retardancy or modify thermal and mechanical properties.
• Chemical Biology Probe: Utilized in the design of enzyme inhibitors and molecular probes for biochemical research.
• Coordination Chemistry: Acts as a chelating agent for various metal ions in research applications.

Basic Information

Product Name	2,3-Dihydro-2-Hydroxy-1H-Isophosphindoline 2-Oxide
CAS No.	20148-17-8
Molecular Formula	C8H9O2P
Molecular Weight	168.13 g/mol
Synonyms	2-Hydroxy-2,3-dihydro-1H-isophosphindole 2-oxide; 1H-Isophosphindoline-2-ol, 2,3-dihydro-, 2-oxide; 2,3-Dihydro-2-hydroxy-1H-isophosphindole 2-oxide; 2-Hydroxyisophosphindoline 2-oxide; Isoindoline, 2-hydroxy-1,3-dihydrophosphindole 2-oxide; Phosphaisoindolin-2-ol, 2-oxide
EINECS	Contact for details

Quality Control

Every batch of 2,3-Dihydro-2-Hydroxy-1H-Isophosphindoline 2-Oxide is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for research and development. A detailed Certificate of Analysis (COA), including results from HPLC, NMR, and other relevant analytical techniques, is available for each lot upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.