Description

4-Bromo-2-Mercaptobenzaldehyde is a versatile and highly functionalized aromatic building block containing both a bromo and a thiol (mercapto) substituent. This unique bifunctional structure makes it a critical intermediate for synthesizing complex heterocycles and advanced pharmaceutical scaffolds. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing sulfur-containing molecules and as a precursor in metal-catalyzed cross-coupling reactions.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those containing benzothiazole, benzothiophene, or other sulfur heterocycles with potential biological activity.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides where the thiol and aldehyde groups offer sites for further chemical modification.
• Ligand Precursor: Serves as a starting material for the preparation of specialized ligands used in catalysis, such as thiolate or Schiff base ligands for transition metal complexes.
• Material Science Research: Employed in the development of organic electronic materials, polymers, and functionalized surfaces where its reactive groups can be used for attachment or polymerization.
• Chemical Biology Probes: Useful for creating probes and linkers in bioconjugation chemistry, leveraging the reactivity of the thiol and aldehyde functional groups.

Basic Information

Product Name	4-Bromo-2-Mercaptobenzaldehyde
CAS No.	20142-20-5
Molecular Formula	C7H5BrOS
Molecular Weight	217.08 g/mol
Synonyms	2-Mercapto-4-bromobenzaldehyde; 4-Bromo-2-sulfanylbenzaldehyde; 4-Bromo-2-thiobenzaldehyde; 4-Bromo-2-mercaptobenzene-1-carbaldehyde; 2-Formyl-5-bromobenzenethiol; 5-Bromo-2-mercaptobenzaldehyde; 20142-20-5; 4-Bromo-2-mercapto-benzaldehyde
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Mercaptobenzaldehyde is produced under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key parameters such as assay, impurity profile, and physical characteristics.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to handle under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to minimize exposure to air and moisture during use.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.