Description

4-(2-Bromoacetyl)Benzonitrile is a versatile and highly reactive organic building block featuring both a bromoacetyl and a nitrile functional group. This bifunctional nature makes it a critical intermediate for synthesizing complex molecules in advanced research and industrial applications. It is primarily sought after by pharmaceutical, agrochemical, and specialty chemical manufacturers for constructing heterocyclic compounds and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various drug candidates, particularly those containing benzofuran, quinoline, or other fused heterocyclic systems.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its reactivity to create complex bioactive structures.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced organic materials.
• Chemical Biology & Proteomics: Employed as an affinity label or a reactive handle for modifying proteins and studying enzyme activity due to the electrophilic bromoacetyl group.
• Ligand Synthesis for Catalysis: Utilized in the preparation of sophisticated ligands for transition metal catalysts used in asymmetric synthesis.
• Dye and Pigment Intermediate: Acts as a building block for synthesizing advanced organic dyes and functional pigments.

Basic Information

Product Name	4-(2-Bromoacetyl)Benzonitrile
CAS No.	20099-89-2
Molecular Formula	C9H6BrNO
Molecular Weight	224.06 g/mol
Synonyms	2-Bromo-1-(4-cyanophenyl)ethanone; p-Cyanophenacyl bromide; 4-Cyanophenacyl bromide; 4-Cyanophenyl bromomethyl ketone; 1-(4-Cyanophenyl)-2-bromoethanone; α-Bromo-4-cyanophenacyl bromide; 4-Acetylbenzonitrile, 2-bromo-; Bromomethyl 4-cyanophenyl ketone
EINECS	Contact for details

Quality Control

Our 4-(2-Bromoacetyl)Benzonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.