Description

3-Trimethylsilylpropynal is a versatile organosilicon building block featuring both a silyl-protected alkyne and an aldehyde functional group. This bifunctional nature makes it a highly valuable intermediate for the synthesis of complex molecules, particularly in pharmaceutical and advanced materials research. It is primarily sought after by R&D chemists and process development scientists in the fine chemical, agrochemical, and electronics industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of heterocyclic compounds, nucleoside analogs, and other bioactive molecules.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, leveraging its reactive aldehyde and alkyne groups.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the synthesis of specialty polymers and silicon-containing advanced materials.
• Ligand and Catalyst Development: Employed in the synthesis of novel organometallic complexes and chiral ligands for asymmetric catalysis.
• Chemical Biology Probes: Useful for bioconjugation and labeling strategies due to its orthogonal reactivity.
• Academic & Industrial R&D: A fundamental reagent for exploratory organic synthesis and methodology development.

Basic Information

Product Name	3-Trimethylsilylpropynal
CAS No.	2975-46-4
Molecular Formula	C7H12OSi
Molecular Weight	140.26 g/mol
Synonyms	3-(Trimethylsilyl)-2-propynal; 3-(Trimethylsilyl)propiolaldehyde; Propiolaldehyde, 3-(trimethylsilyl)-; Trimethylsilylpropiolaldehyde; TMS-propynal; 2-Propynal, 3-(trimethylsilyl)-; 3-Trimethylsilylpropiolaldehyde
EINECS	221-003-8

Quality Control

Our 3-Trimethylsilylpropynal is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with your specifications and industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.