Description

2-Propanone, 1-Fluoro-3-Phenoxy- is a specialized fluorinated ketone building block, also known by its CAS number 2967-88-6. This compound is valued for its unique molecular structure, which combines a reactive acetone backbone with a fluorinated phenoxy group, making it a versatile intermediate for advanced synthesis. It is primarily sought by R&D chemists and process development teams in the pharmaceutical and agrochemical sectors for constructing complex molecules where fluorine introduction is critical for modulating biological activity, metabolic stability, and physicochemical properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom enhances lipophilicity and environmental stability.
• Material Science Research: Serves as a precursor for specialty polymers and liquid crystals, contributing to the development of materials with specific optical or surface properties.
• Organic Synthesis Building Block: Employed in academic and industrial laboratories for constructing complex organic frameworks, including heterocycles and chiral molecules, via reactions at the ketone or aromatic sites.
• Fluorine Chemistry Studies: Acts as a model compound in methodological development for studying fluorination reactions and the behavior of fluorinated functional groups.

Basic Information

Product Name	2-Propanone, 1-Fluoro-3-Phenoxy-
CAS No.	2967-88-6
Molecular Formula	C9H9FO2
Molecular Weight	168.16 g/mol
Synonyms	1-Fluoro-3-phenoxyacetone; 3-Phenoxy-1-fluoroacetone; 1-Fluoro-3-phenoxy-2-propanone; Phenoxyfluoromethyl methyl ketone; α-Fluoro-β-phenoxyacetone; 2-Propanone, 1-fluoro-3-phenoxy-; (Fluoromethyl)(phenoxymethyl) ketone; 3-Phenoxy-1-fluoropropan-2-one
EINECS	Contact for details

Quality Control

Every batch of 2-Propanone, 1-Fluoro-3-Phenoxy- is produced and tested under a strict quality management system. We ensure high purity and consistency through advanced analytical techniques including GC, HPLC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider maintaining under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Individual ≤ 1.0%, Total ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.