Description

Ethyl Chlorothioformate is a versatile organosulfur reagent primarily used as a key building block in organic synthesis. Its high reactivity as an acylating and thiocarbonylating agent makes it invaluable for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce thioester or thiocarbamate functionalities.

Application

• Pharmaceutical Intermediate: Critical for the synthesis of active pharmaceutical ingredients (APIs), particularly those containing thioester or thiocarbonate moieties.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides where the thiocarbonyl group is a key structural component.
• Peptide Chemistry: Serves as a coupling agent or protecting group reagent in the synthesis of modified peptides and peptidomimetics.
• Polymer Chemistry: Acts as a monomer or modifier in the production of specialty polymers and resins with unique properties.
• Chemical Research: A fundamental reagent in academic and industrial R&D for exploring new synthetic methodologies and heterocyclic compound formation.
• Dye and Pigment Manufacturing: Employed in the synthesis of sulfur-containing dyes and organic pigments.

Basic Information

Product Name	Ethyl Chlorothioformate
CAS No.	2941-64-2
Molecular Formula	C3H5ClOS
Molecular Weight	124.59 g/mol
Synonyms	Chlorothioformic Acid O-Ethyl Ester; Ethoxycarbonylsulfenyl Chloride; Ethyl Chloromethanethioate; Carbonochloridothioic Acid O-Ethyl Ester; Thiocarbonyl Chloride O-Ethyl Ester; Ethyl Chlorothiolformate; O-Ethyl Chlorothioformate
EINECS	220-937-8

Quality Control

Our Ethyl Chlorothioformate is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere to maintain stability. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	1.20 - 1.25 g/mL
Refractive Index (n20D)	1.470 - 1.480

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.