Description

Bis(Isopropyloxy)[[2,6-Bis(1,1-Dimethylethyl)-4-Methylphenyl]Oxy]Borane is a specialized organoboron compound that serves as a versatile reagent in advanced synthetic chemistry. Its value lies in its role as a protected boronic acid derivative, offering enhanced stability and controlled reactivity for critical coupling reactions. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science sectors who require reliable building blocks for complex molecule synthesis.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key precursor for generating active boronic acid species in situ for forming carbon-carbon bonds.
• Pharmaceutical Intermediate Synthesis: Used in the research and production of active pharmaceutical ingredients (APIs), particularly for complex, multi-step syntheses.
• Agrochemical Development: Employed in creating novel herbicides, fungicides, and insecticides that require specific boron-containing motifs.
• Advanced Materials Research: Serves as a monomer or functionalization agent in the development of organic electronic materials and polymers.
• Ligand and Catalyst Preparation: Utilized in the synthesis of novel ligands for transition metal catalysis.
• Process Chemistry & Scale-Up: Provides a stable, storable alternative to sensitive boronic acids for large-scale manufacturing processes.

Basic Information

Product Name	Bis(Isopropyloxy)[[2,6-Bis(1,1-Dimethylethyl)-4-Methylphenyl]Oxy]Borane
CAS No.	2929-87-5
Molecular Formula	C₂₁H₃₇BO₃
Molecular Weight	348.33 g/mol
Synonyms	Bis(isopropoxy)(2,6-di-tert-butyl-4-methylphenoxy)borane; (2,6-Di-tert-butyl-4-methylphenoxy)bis(isopropoxy)borane; Boron, bis(1-methylethoxy)[(2,6-bis(1,1-dimethylethyl)-4-methylphenyl)oxy]-; B-Isopropoxy B-(2,6-di-tert-butyl-4-methylphenoxy)borinic Acid Isopropyl Ester; Protected BHT-Boronic Acid Derivative
EINECS	Contact for details

Quality Control

Our production of Bis(Isopropyloxy)[[2,6-Bis(1,1-Dimethylethyl)-4-Methylphenyl]Oxy]Borane adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for demanding synthetic applications. All material is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with cGMP and ISO 9001 standards where required, and specifications can be tailored to meet specific project needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (NMR)	≥ 95.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.