Description

2-Amino-3-[3-(Trifluoromethyl)Phenyl]Sulfanyl-Propanoic Acid is a specialized non-proteinogenic amino acid derivative featuring a trifluoromethylphenylthioether side chain. This compound matters as a versatile and high-value pharmaceutical intermediate and building block for medicinal chemistry research. It is primarily needed by R&D chemists and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors for synthesizing novel bioactive molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in protease inhibitor and enzyme modulator research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore the impact of the trifluoromethyl and thioether groups on bioactivity and metabolic stability.
• Agrochemical Development: Serves as a precursor in the design of new herbicides, fungicides, or plant growth regulators leveraging its unique chemical scaffold.
• Peptidomimetics: Incorporated into peptide analogs to enhance lipophilicity, membrane permeability, and resistance to enzymatic degradation.
• Chemical Biology Probes: Utilized in the development of activity-based probes or affinity labels for studying enzyme function and protein interactions.
• Material Science: Potential monomer or additive for creating specialized polymers with specific surface or electronic properties.

Basic Information

Product Name	2-Amino-3-[3-(Trifluoromethyl)Phenyl]Sulfanyl-Propanoic Acid
CAS No.	2928-03-2
Molecular Formula	C10H10F3NO2S
Molecular Weight	265.25 g/mol
Synonyms	3-[(3-Trifluoromethyl)phenyl]thio-L-alanine; 2-Amino-3-((3-(trifluoromethyl)phenyl)thio)propanoic acid; (2S)-2-Amino-3-[[3-(trifluoromethyl)phenyl]sulfanyl]propanoic acid; β-[(3-Trifluoromethylphenyl)thio]alanine; L-3-(3-Trifluoromethylphenylthio)alanine; 2-Amino-3-(3-trifluoromethylphenylthio)propionic acid; α-Amino-β-((3-(trifluoromethyl)phenyl)thio)propionic acid
EINECS	Contact for details

Quality Control

Our 2-Amino-3-[3-(Trifluoromethyl)Phenyl]Sulfanyl-Propanoic Acid is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area%)	≥ 98.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.