Description

4-(Trimethylsilyl)Butan-1-Ol is a versatile organosilicon compound featuring a terminal hydroxyl group protected by a trimethylsilyl moiety. This unique structure makes it a valuable synthetic intermediate and protecting group reagent in advanced organic synthesis. It is primarily utilized by pharmaceutical, agrochemical, and specialty chemical manufacturers for the development of complex molecules where selective protection and functional group manipulation are required.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly where silicon-containing groups are needed for stability or bioavailability.
• Agrochemical Synthesis: Serves as a key building block in the production of advanced pesticides, herbicides, and plant growth regulators.
• Polymer & Material Science: Acts as a monomer or modifier in the synthesis of silicon-based polymers, resins, and specialty coatings to impart specific surface properties.
• Organic Synthesis Reagent: Functions as a protected alcohol synthon in multi-step organic reactions, including Grignard reactions, nucleophilic substitutions, and cross-coupling chemistry.
• Liquid Crystal & OLED Material Production: Employed in the manufacturing of silicon-based components for electronic display and lighting technologies.
• Adhesive & Sealant Formulations: Used as an additive to modify the curing characteristics and adhesion properties of silicone-based products.

Basic Information

Product Name	4-(Trimethylsilyl)Butan-1-Ol
CAS No.	2917-40-0
Molecular Formula	C7H18OSi
Molecular Weight	146.30 g/mol
Synonyms	4-(Trimethylsilyl)-1-butanol; 1-Butanol, 4-(trimethylsilyl)-; 4-Trimethylsilylbutan-1-ol; (4-Hydroxybutyl)trimethylsilane; Trimethyl(4-hydroxybutyl)silane; TMS-Butanol; γ-Trimethylsilylbutyl alcohol
EINECS	220-852-5

Quality Control

Our production of 4-(Trimethylsilyl)Butan-1-Ol adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistent performance. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO 9001 standards for manufacturing and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.4280 - 1.4320
Density (20°C)	0.83 - 0.87 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.