Description

2,2,2-Trichloroacetophenone is a specialized organic compound featuring a trichloromethyl ketone group, making it a versatile intermediate for fine chemical synthesis. Its primary commercial value lies in its role as a key building block for the production of pharmaceuticals, agrochemicals, and advanced materials. This product is essential for R&D laboratories and manufacturing facilities in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients or functional compounds.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those containing substituted acetophenone or benzophenone moieties.
• Agrochemical Synthesis: Used in the manufacturing of herbicides, fungicides, and plant growth regulators where the trichloromethyl group is a key functional element.
• Organic Synthesis Reagent: Serves as a starting material or reagent in Friedel-Crafts acylation and other reactions to introduce the trichloroacetyl functional group into aromatic systems.
• Photoinitiator Production: Acts as a raw material in the manufacture of photoinitiators used in UV-curable inks, coatings, and adhesives.
• Ligand and Catalyst Preparation: Utilized for the preparation of specialized ligands and organometallic catalysts in asymmetric synthesis.
• Research & Development: A valuable compound for academic and industrial R&D in medicinal chemistry and material science for exploring new chemical entities.

Basic Information

Product Name	2,2,2-Trichloroacetophenone
CAS No.	2902-69-4
Molecular Formula	C8H5Cl3O
Molecular Weight	223.48 g/mol
Synonyms	α,α,α-Trichloroacetophenone; Phenacyltrichloride; Trichloromethyl Phenyl Ketone; 2,2,2-Trichloro-1-phenylethanone; Phenyl Trichloromethyl Ketone; 1-Phenyl-2,2,2-trichloroethanone; Acetophenone, 2,2,2-trichloro-; TCA
EINECS	220-824-0

Quality Control

Our 2,2,2-Trichloroacetophenone is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chromatography and spectroscopy, to ensure it meets precise purity and identity specifications. A Certificate of Analysis (COA) detailing the results for all critical parameters is provided with every shipment to guarantee traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and reducing agents. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to minimize moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	36°C - 40°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.