Description

5'-Chloro-2'-Hydroxypropiophenone is a versatile aromatic ketone building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both a chloro and a phenolic hydroxyl group, makes it a critical intermediate for constructing more complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those with benzophenone or propiophenone backbones.
• Agrochemical Synthesis: Used in the research and production of herbicides, fungicides, and other crop protection agents.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex molecules via reactions such as alkylation, acylation, and cyclization.
• Fine Chemical Production: Serves as an intermediate in the manufacture of dyes, pigments, and specialty performance chemicals.
• Material Science Research: Investigated for potential use in the development of novel polymers and advanced organic materials.

Basic Information

Product Name	5'-Chloro-2'-Hydroxypropiophenone
CAS No.	2892-16-2
Molecular Formula	C9H9ClO2
Molecular Weight	184.62 g/mol
Synonyms	1-(5-Chloro-2-hydroxyphenyl)propan-1-one; 2-Hydroxy-5-chloropropiophenone; 5-Chloro-2-hydroxypropiophenone; 5-Chloro-2'-hydroxypropiophenone; 2'-Hydroxy-5'-chloropropiophenone; 1-Propanone, 1-(5-chloro-2-hydroxyphenyl)-; o-Hydroxy-p-chloropropiophenone
EINECS	220-777-9

Quality Control

Our 5'-Chloro-2'-Hydroxypropiophenone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates for GMP and research purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	78°C - 82°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.