Description

4-(4-Hydroxyphenoxy)-3,5-Diiodo-Benzaldehyde is a high-purity iodinated aromatic aldehyde derivative, serving as a critical advanced pharmaceutical intermediate and versatile building block in organic synthesis. Its unique molecular structure, featuring both phenolic ether and aldehyde functional groups, enables precise chemical modifications essential for developing complex molecules. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for applications in drug discovery and material science.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in thyroid hormone analogs and X-ray contrast media.
• Organic Synthesis Reagent: Used in cross-coupling reactions, such as Suzuki and Heck reactions, to construct complex biaryl and heterocyclic structures.
• Agrochemical Research: Intermediate in the development of new herbicides and plant growth regulators with specific modes of action.
• Liquid Crystal & Polymer Chemistry: Serves as a monomer or precursor for creating iodinated polymers and liquid crystal materials with specific optical properties.
• Diagnostic Agent Precursor: Used in the research and development of iodinated compounds for medical imaging and diagnostic applications.
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for studying biological processes due to its iodine atoms and reactive aldehyde group.

Basic Information

Product Name	4-(4-Hydroxyphenoxy)-3,5-Diiodo-Benzaldehyde
CAS No.	2828-49-1
Molecular Formula	C13H8I2O3
Molecular Weight	465.01 g/mol
Synonyms	3,5-Diiodo-4-(4-hydroxyphenoxy)benzaldehyde; 4-(4-Hydroxyphenoxy)-3,5-diiodobenzaldehyde; Benzaldehyde, 4-(4-hydroxyphenoxy)-3,5-diiodo-; 3,5-Diiodo-4-(p-hydroxyphenoxy)benzaldehyde; 4-(p-Hydroxyphenoxy)-3,5-diiodobenzaldehyde; 2828-49-1 (CAS); 4-(4-Hydroxy-phenoxy)-3,5-diiodo-benzaldehyde
EINECS	Contact for details

Quality Control

Our 4-(4-Hydroxyphenoxy)-3,5-Diiodo-Benzaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP-grade requirements. Specifications can be tailored to meet specific project needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.