Description

4-(Dimethylamino)-2-Methyl-2-Phenylbutanenitrile is a versatile organic intermediate featuring a nitrile group and a tertiary amine functionality. This compound is valued for its role as a key building block in the synthesis of complex molecules, particularly in pharmaceutical and fine chemical research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing active pharmaceutical ingredients (APIs) and other high-value compounds.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of various drug candidates and active pharmaceutical ingredients (APIs), particularly those requiring a substituted phenylbutanenitrile scaffold.
• Agrochemical Synthesis: Used as a building block for developing advanced pesticides, herbicides, and plant growth regulators.
• Fine Chemical Production: Serves as a versatile intermediate in the manufacture of dyes, pigments, and other performance chemicals.
• Research & Development: Employed in academic and industrial R&D labs for method development, structure-activity relationship (SAR) studies, and novel compound library synthesis.
• Chemical Synthesis: Utilized in organic transformations, including nucleophilic additions and cyano-group manipulations, to create more complex molecular architectures.

Basic Information

Product Name	4-(Dimethylamino)-2-Methyl-2-Phenylbutanenitrile
CAS No.	2809-43-0
Molecular Formula	C14H18N2
Molecular Weight	214.31 g/mol
Synonyms	2-Phenyl-2-methyl-4-(dimethylamino)butyronitrile; 4-(Dimethylamino)-2-methyl-2-phenylbutyronitrile; α-Methyl-α-phenyl-γ-(dimethylamino)butyronitrile; 2-Methyl-2-phenyl-4-(dimethylamino)butanenitrile; DMAPBN; NSC 334365; γ-(Dimethylamino)-α-methylbenzenepropanenitrile
EINECS	220-552-9

Quality Control

Our 4-(Dimethylamino)-2-Methyl-2-Phenylbutanenitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.