Description

1-Bromo-3-((trifluoromethyl)sulfonyl)benzene is a high-value, multi-functional aromatic building block featuring both bromo and triflyl substituents. This compound matters for its unique reactivity profile, enabling precise cross-coupling reactions and serving as a versatile synthon for complex molecule construction. It is primarily needed by researchers and process chemists in the pharmaceutical and agrochemical industries for developing active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring sulfonamide or aryl bromide functionalities.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the trifluoromethanesulfonyl group enhances biological activity and stability.
• Material Science: Serves as a monomer or building block for advanced polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The aryl bromide moiety is an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands and organocatalysts for asymmetric synthesis.
• Chemical Research: A valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and creating compound libraries.

Basic Information

Product Name	1-Bromo-3-((trifluoromethyl)sulfonyl)benzene
CAS No.	2728-70-3
Molecular Formula	C7H4BrF3O2S
Molecular Weight	289.07 g/mol
Synonyms	3-Bromophenyl trifluoromethyl sulfone; 1-Bromo-3-(trifluoromethylsulfonyl)benzene; m-Bromophenyl trifluoromethyl sulfone; 3-Bromo-α,α,α-trifluorotoluene-p-sulfone; Benzene, 1-bromo-3-[(trifluoromethyl)sulfonyl]-; 3-Bromo-α,α,α-trifluoro-p-toluenesulfone; 3-Bromo-α,α,α-trifluoro-4-methylbenzenesulfone
EINECS	Contact for details

Quality Control

Our 1-Bromo-3-((trifluoromethyl)sulfonyl)benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.