Description

Acetamide, 2,2,2-Trifluoro-n-(2-Methylphenyl)- is a specialized fluorinated acetamide derivative, recognized for its unique trifluoromethyl group and aromatic substitution. This compound is valued for its role as a versatile synthetic intermediate, particularly in the development of advanced pharmaceuticals and agrochemicals where fluorine incorporation is critical for enhancing metabolic stability and biological activity. It is primarily sought by research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds requiring a trifluoroacetamide moiety.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where fluorination improves efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and metal-catalyzed reactions.
• Material Science Research: Employed in the development of novel fluorinated polymers and advanced materials with specific thermal or chemical resistance properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological systems and enzyme mechanisms.

Basic Information

Product Name	Acetamide, 2,2,2-Trifluoro-n-(2-Methylphenyl)-
CAS No.	2727-68-6
Molecular Formula	C10H10F3NO
Molecular Weight	217.19 g/mol
Synonyms	N-(2-Methylphenyl)-2,2,2-trifluoroacetamide; 2,2,2-Trifluoro-N-(o-tolyl)acetamide; 2-Methyl-2',2',2'-trifluoroacetanilide; o-Tolyltrifluoroacetamide; 2-(Trifluoroacetamido)toluene; α,α,α-Trifluoro-o-acetotoluidide; N-(2-Methylphenyl)trifluoroacetamide
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for purity, related substances, and residual solvents are available upon request. We adhere to cGMP principles for the manufacture of materials intended for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.