Description

2,2-Dichloroacetophenone is a versatile organic building block characterized by its reactive carbonyl and halogen functionalities. This compound matters for its role as a key intermediate in the synthesis of more complex molecules, particularly in the pharmaceutical and agrochemical sectors. Industries requiring fine chemical synthesis, including pharmaceutical R&D and specialty chemical manufacturing, are the primary users of this high-purity intermediate.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds with ketone or phenone backbones.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and pesticides, leveraging its reactive dichloroacetyl group.
• Organic Synthesis Reagent: Serves as a versatile building block for Friedel-Crafts acylation and other reactions to introduce the dichloroacetylphenyl moiety.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new synthetic pathways and novel compound libraries.
• Dye and Pigment Intermediate: Acts as a starting material in the synthesis of certain specialized dyes and organic pigments.

Basic Information

Product Name	2,2-Dichloroacetophenone
CAS No.	2648-61-5
Molecular Formula	C8H6Cl2O
Molecular Weight	189.04 g/mol
Synonyms	ω,ω-Dichloroacetophenone; Phenacylidene Chloride; Dichloromethyl Phenyl Ketone; α,α-Dichloroacetophenone; 2,2-Dichloro-1-phenylethanone; Phenyl Dichloromethyl Ketone; NSC 406579; Dichlorophenacyl
EINECS	220-167-7

Quality Control

Our 2,2-Dichloroacetophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque or amber packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	60°C - 64°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.