Description

1,4-Bis(Chlorodifluoromethyl)Benzene is a specialized fluorinated aromatic building block of significant interest in advanced chemical synthesis. This compound matters for its role as a key precursor in the development of high-performance materials and active pharmaceutical ingredients (APIs), where its unique difluoromethyl chloride groups enable precise molecular modifications. It is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty polymer industries seeking to incorporate fluorinated motifs for enhanced properties.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing novel drug candidates, particularly those requiring fluorinated aromatic cores to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where fluorine introduction can improve efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a key monomer in the synthesis of fluorinated liquid crystals and organic light-emitting diode (OLED) materials, contributing to improved electronic properties and stability.
• Specialty Polymer Modifier: Incorporated into high-performance polymers, such as polyarylates or polyimides, to enhance thermal stability, chemical resistance, and dielectric properties.
• Fluorinated Surfactant Precursor: Acts as a starting material for creating surfactants with unique surface activity and stability for demanding industrial applications.
• Organic Synthesis Reagent: Employed in cross-coupling reactions and nucleophilic substitution chemistry to introduce the -CF2Cl functional group into complex molecules.

Basic Information

Product Name	1,4-Bis(Chlorodifluoromethyl)Benzene
CAS No.	2629-68-7
Molecular Formula	C8H4Cl2F4
Molecular Weight	247.02 g/mol
Synonyms	p-Bis(chlorodifluoromethyl)benzene; 1,4-Bis(chlorodifluoromethyl)benzene; α,α,α',α'-Tetrachloro-α,α,α',α'-tetrafluoro-p-xylene; Benzene, 1,4-bis(chlorodifluoromethyl)-; p-Xylylene tetrachlorotetrafluoride; 1,4-Di(chlorodifluoromethyl)benzene; p-(Chlorodifluoromethyl)benzyl chloride (related); EINECS 220-104-6
EINECS	220-104-6

Quality Control

Our 1,4-Bis(Chlorodifluoromethyl)Benzene is produced and tested under a strict quality management system. Each batch undergoes rigorous analytical testing, including chromatography (HPLC/GC) and spectroscopy (NMR, IR), to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specification parameters are provided with every shipment. We support compliance with relevant frameworks for industrial and research use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.