Description

1-Methoxycarbonylethylidenetriphenylphosphorane is a specialized Wittig reagent, a key organophosphorus compound used in synthetic organic chemistry. Its primary value lies in its ability to facilitate the stereoselective synthesis of α,β-unsaturated esters, a crucial transformation for building complex molecular frameworks. This reagent is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries who require high-purity intermediates for developing active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate Synthesis: Key reagent for constructing olefinic bonds in drug discovery and development, particularly for creating α,β-unsaturated ester motifs found in many active pharmaceutical ingredients (APIs).
• Agrochemical Production: Used in the synthesis of complex molecules for herbicides, fungicides, and insecticides, where specific alkene geometry is critical for biological activity.
• Fine Chemical and Specialty Chemical Manufacturing: Employed in the production of flavors, fragrances, dyes, and other high-value chemicals requiring precise olefination reactions.
• Academic and R&D Laboratories: A fundamental tool for methodological development in organic synthesis and for preparing novel compounds in material science research.
• Polymer Science: Potential use in the synthesis of monomers containing specific unsaturated ester functionalities for advanced polymeric materials.

Basic Information

Product Name	1-Methoxycarbonylethylidenetriphenylphosphorane
CAS No.	2605-68-7
Molecular Formula	C22H21O2P
Molecular Weight	348.38 g/mol
Synonyms	(Methoxycarbonylmethylene)triphenylphosphorane; Methyl (triphenylphosphoranylidene)acetate; Triphenylphosphoranylidene methyl acetate; Methyl (triphenylphosphoranylidene)ethanoate; Wittig reagent methyl (triphenylphosphoranylidene)acetate; Phosphorane, (methoxycarbonylmethylene)triphenyl-; Acetic acid, 2-(triphenylphosphoranylidene)-, methyl ester
EINECS	Contact for details

Quality Control

Our 1-Methoxycarbonylethylidenetriphenylphosphorane is manufactured under strict quality protocols to ensure batch-to-batch consistency and high reactivity. Each lot is analyzed to confirm identity, purity, and suitability for demanding synthetic applications. A comprehensive Certificate of Analysis (COA) detailing specifications such as assay (by NMR or HPLC), melting point, and appearance is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C or as specified on the label. This material is hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air and moisture must be avoided to maintain stability and reactivity.

Specification

Item	Specification
Appearance	White to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (NMR/HPLC)	≥ 97.0%
Melting Point	168 - 172 °C
Solubility	Soluble in common organic solvents (e.g., THF, DCM)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.