Description

8-Acetyl-7-Hydroxy-4-Methylcoumarin is a functionalized coumarin derivative, a versatile organic intermediate prized for its unique photophysical and chemical properties. This compound is essential for synthesizing advanced materials and fine chemicals, offering a reactive acetyl group and phenolic hydroxyl for further functionalization. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel active ingredients and functional dyes.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly those with potential anticoagulant, anti-inflammatory, or fluorescent probe activities.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging the coumarin scaffold's bioactivity.
• Organic Light-Emitting Diodes (OLEDs): Acts as a precursor for electron-transport materials or emissive dopants due to its rigid, planar structure and potential for fluorescence.
• Fluorescent Dyes and Sensors: Employed in the creation of chemosensors and biological labeling agents, where its hydroxy and acetyl groups allow for attachment to various substrates.
• UV Absorbers and Stabilizers: Incorporated into polymer formulations to enhance light stability, as the coumarin core can absorb harmful UV radiation.
• Fine Chemical Research: A valuable reagent in academic and industrial R&D for exploring new organic reactions and constructing complex heterocyclic systems.

Basic Information

Item	Detail
Product Name	8-Acetyl-7-Hydroxy-4-Methylcoumarin
CAS No.	2555-29-5
Molecular Formula	C₁₂H₁₀O₄
Molecular Weight	218.21 g/mol
Synonyms	7-Hydroxy-8-acetyl-4-methylcoumarin; 7-Hydroxy-4-methyl-8-acetylcoumarin; 4-Methyl-7-hydroxy-8-acetylcoumarin; 8-Acetyl-4-methylumbelliferone; 8-Acetyl-4-methyl-7-hydroxycoumarin; 8-Acetyl-7-hydroxy-4-methyl-2H-chromen-2-one
EINECS	Contact for details

Quality Control

Our 8-Acetyl-7-Hydroxy-4-Methylcoumarin is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets precise customer specifications. Certificates of Analysis (COA) detailing all quality parameters are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.