Description

Trichloromethanesulfonyl Chloride is a highly reactive and versatile sulfonylating agent, crucial for introducing the trichloromethanesulfonyl (tresyl) group into target molecules. Its primary value lies in its ability to act as a key synthetic intermediate in the preparation of pharmaceuticals, agrochemicals, and advanced materials. This compound is essential for research chemists and process development scientists in the pharmaceutical, fine chemical, and specialty polymer industries seeking to create novel sulfonamide derivatives or functionalize surfaces and polymers.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those containing sulfonamide moieties.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and other crop protection agents.
• Polymer Modification: Serves as a functionalizing agent for polymers and resins to impart specific chemical properties.
• Bioconjugation & Protein Chemistry: Employed in the activation of hydroxyl groups on surfaces or polymers for subsequent coupling with amines, useful in chromatography media and biosensor development.
• Fine Chemical Synthesis: A versatile reagent for constructing complex organic molecules in research and development laboratories.
• Dye and Pigment Manufacturing: Intermediate in the synthesis of specialty dyes and colorants.

Basic Information

Product Name	Trichloromethanesulfonyl Chloride
CAS No.	2547-61-7
Molecular Formula	CCl4O2S
Molecular Weight	229.90 g/mol
Synonyms	Trichloromethanesulfonyl chloride; Perchloromethylsulfonyl chloride; Trichloromethylsulfonyl chloride; Tresyl chloride; Trichloromethanesulphonyl chloride; CCl3SO2Cl; NSC 401106
EINECS	219-823-7

Quality Control

Our Trichloromethanesulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including assay by titration and impurity profiling, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and relevant specifications is provided with every shipment to guarantee reliable performance in your synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC or Titration)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.