Description

4-(Trifluoromethoxy)Phenyl Methyl Sulfide is a specialized organosulfur compound featuring a trifluoromethoxy-substituted aromatic ring. This high-purity intermediate is valued for its unique combination of lipophilicity and electronic properties imparted by the sulfur and fluorine atoms, making it a critical building block in advanced chemical synthesis. It is primarily sought by R&D and production teams in the pharmaceutical and agrochemical sectors for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the trifluoromethoxy group enhances biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorine-containing liquid crystals for display technologies.
• Functional Material Development: Employed in creating organic electronic materials, such as semiconductors and charge-transport layers.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to construct complex biaryl systems.
• Chemical Research: Utilized in academic and industrial labs to study structure-activity relationships (SAR) and novel reaction pathways involving sulfur-containing aromatics.

Basic Information

Product Name	4-(Trifluoromethoxy)Phenyl Methyl Sulfide
CAS No.	2546-45-4
Molecular Formula	C8H7F3OS
Molecular Weight	208.20 g/mol
Synonyms	1-(Methylthio)-4-(trifluoromethoxy)benzene; Methyl 4-(Trifluoromethoxy)phenyl Sulfide; p-(Trifluoromethoxy)thioanisole; 4-(Trifluoromethoxy)thioanisole; (4-(Trifluoromethoxy)phenyl)(methyl)sulfane; 4-Methylsulfanyl-1-(trifluoromethoxy)benzene; α,α,α-Trifluoro-p-(methylthio)anisole
EINECS	Contact for details

Quality Control

Our 4-(Trifluoromethoxy)Phenyl Methyl Sulfide is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. We provide full traceability and a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.