Description

2-Chloro-3-Methoxypropionic Acid is a versatile bifunctional organic acid chloride derivative, serving as a key chiral building block and reactive intermediate in advanced chemical synthesis. Its molecular structure, featuring both a reactive acid chloride and a protected ether group, makes it invaluable for constructing complex molecules with high stereochemical control. This compound is essential for research and production in the pharmaceutical and agrochemical sectors, where it is used to synthesize active ingredients, chiral ligands, and specialty polymers.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of chiral active pharmaceutical ingredients (APIs), particularly for cardiovascular and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where its chloro and methoxy groups enable specific biological activity.
• Chiral Ligand & Catalyst Preparation: Employed for the synthesis of novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Polymer Modification: Acts as a functional monomer or cross-linking agent for specialty polymers, including coatings and resins with tailored properties.
• Organic Synthesis Building Block: Utilized in academic and industrial R&D for constructing complex organic molecules, including natural product analogs.
• Fine Chemical Production: Serves as an intermediate in the manufacture of dyes, flavors, and other high-value fine chemicals.

Basic Information

Product Name	2-Chloro-3-Methoxypropionic Acid
CAS No.	2544-05-0
Molecular Formula	C4H7ClO3
Molecular Weight	138.55 g/mol
Synonyms	2-Chloro-3-methoxypropanoic Acid; 3-Methoxy-2-chloropropionic Acid; α-Chloro-β-methoxypropionic Acid; (RS)-2-Chloro-3-methoxypropionic Acid; DL-2-Chloro-3-methoxypropionic Acid; 2544-05-0; Propionic acid, 2-chloro-3-methoxy-
EINECS	219-819-9

Quality Control

Every batch of our 2-Chloro-3-Methoxypropionic Acid is produced under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) that detail key parameters such as assay, chiral purity (if applicable), and impurity profiles. Our quality commitment aligns with cGMP principles where required, ensuring reliability for critical applications in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its nature as a strong acid/organic solvent, store separately from bases, oxidizing agents, and reactive metals. Use appropriate corrosion-resistant storage materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Specific Rotation (if chiral)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.