Description

Methanesulfonylacetic Acid is a versatile sulfonyl-containing organic acid building block with significant synthetic utility. Its reactive carboxylic acid and electron-withdrawing sulfonyl group make it a valuable intermediate for constructing complex molecules in pharmaceutical and agrochemical research. This compound is essential for chemists in fine chemical synthesis, particularly for the development of active pharmaceutical ingredients (APIs) and specialty chemicals. Its properties facilitate key reactions like condensations and nucleophilic substitutions.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially those requiring a sulfonylacetic acid moiety.
• Agrochemical Synthesis: Used in the research and production of herbicides, fungicides, and plant growth regulators.
• Peptide Mimetics & Conjugation: Serves as a linker or spacer in the design of peptide analogs and bioconjugates.
• Polymer Chemistry: Acts as a monomer or modifier for creating functional polymers with specific acid or sulfone groups.
• Organic Synthesis Reagent: Employed in various condensation reactions and as a precursor for other sulfonyl-based reagents.
• Chemical Research & Development: A valuable tool for medicinal chemistry and process development in R&D laboratories.

Basic Information

Product Name	Methanesulfonylacetic Acid
CAS No.	2516-97-4
Molecular Formula	C3H6O4S
Molecular Weight	138.14 g/mol
Synonyms	2-(Methylsulfonyl)acetic Acid; (Methylsulfonyl)acetic Acid; Methanesulfonic Acid, Acetic Acid Anhydride; Acetic Acid, 2-(Methylsulfonyl)-; NSC 403016; Methylsulfonylacetic Acid; Mesylacetic Acid
EINECS	219-744-7

Quality Control

Our Methanesulfonylacetic Acid is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including assay (HPLC), identification (IR, NMR), and impurity profiling, to ensure it meets the high-purity standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	92 - 96 °C
Loss on Drying	≤ 1.0 %
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.