Description

2-Bromo-4'-Hydroxyacetophenone is a versatile brominated aromatic ketone that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both a reactive bromine atom and a phenolic hydroxyl group, makes it a valuable intermediate for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries, where it is used to develop active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those with brominated aromatic cores.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and other crop protection agents.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing specialized ligands used in catalytic processes.
• Material Science Research: Employed in the creation of novel organic compounds for electronic or optical materials.
• Chemical Derivatization: Utilized in academic and industrial R&D for structure-activity relationship (SAR) studies and molecular modification.
• Fine Chemical Production: Acts as a building block for dyes, pigments, and other high-value specialty chemicals.

Basic Information

Product Name	2-Bromo-4'-Hydroxyacetophenone
CAS No.	2491-38-5
Molecular Formula	C8H7BrO2
Molecular Weight	215.05 g/mol
Synonyms	1-(4-Hydroxyphenyl)-2-bromoethanone; 2-Bromo-1-(4-hydroxyphenyl)ethanone; 4'-Hydroxy-2-bromoacetophenone; p-Hydroxy-α-bromoacetophenone; 2-Bromo-4'-hydroxyacetophenone; 2-Bromo-4-hydroxyacetophenone; α-Bromo-4-hydroxyacetophenone; Bromo(4-hydroxyphenyl)methanone
EINECS	219-667-5

Quality Control

Our 2-Bromo-4'-Hydroxyacetophenone is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring reliable and traceable raw materials for GMP or research purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	148°C - 152°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.