Description

2-Bromo-2′-Hydroxyacetophenone is a versatile brominated aromatic ketone that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both a bromine substituent and a phenolic hydroxyl group, makes it a valuable building block for constructing complex molecular architectures. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those with benzofuran or related heterocyclic cores.
• Agrochemical Synthesis: Used in the research and production of herbicides, fungicides, and other crop protection agents.
• Organic Synthesis Building Block: Employed in Suzuki, Heck, and other cross-coupling reactions to introduce functionalized aryl groups.
• Ligand and Catalyst Preparation: Useful for synthesizing specialized ligands for metal catalysis and coordination chemistry.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers and advanced organic materials.
• Chemical Research & Development: A standard reagent in R&D laboratories for method development and exploring new synthetic pathways.

Basic Information

Product Name	2-Bromo-2′-Hydroxyacetophenone
CAS No.	2491-36-3
Molecular Formula	C8H7BrO2
Molecular Weight	215.05 g/mol
Synonyms	2'-Hydroxy-2-bromoacetophenone; 1-(2-Bromophenyl)-2-hydroxyethanone; 2-Bromo-2'-hydroxyacetophenone; o-Bromo-2'-hydroxyacetophenone; 2-Bromo-2-hydroxyacetophenone; 2-Bromophenacyl alcohol; α-Bromo-2'-hydroxyacetophenone; (2-Bromophenyl)(hydroxy)methanone
EINECS	219-667-6

Quality Control

Our 2-Bromo-2′-Hydroxyacetophenone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	78°C - 82°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.