Description

4-Pyrrolidinopyridine is a highly effective and versatile organocatalyst and ligand widely used in organic synthesis. This compound is valued for its ability to significantly accelerate acylation and other nucleophilic substitution reactions, often under mild conditions. It is an essential reagent for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking to improve reaction efficiency and yield.

Application

• As a powerful acyl transfer catalyst in the synthesis of esters, amides, and peptides.
• As a ligand in transition metal-catalyzed coupling reactions (e.g., Suzuki, Heck).
• In the synthesis of active pharmaceutical ingredients (APIs) and complex drug intermediates.
• For the preparation of fine chemicals and specialty materials requiring high selectivity.
• As a catalyst in polymerization and materials science research.
• In academic and industrial R&D for methodological development in organic chemistry.

Basic Information

Product Name	4-Pyrrolidinopyridine
CAS No.	2456-81-7
Molecular Formula	C9H12N2
Molecular Weight	148.21 g/mol
Synonyms	4-(1-Pyrrolidinyl)pyridine; 4-Pyrrolidinopyridine; 4-Pyrrolidino pyridine; 4-Pyridylpyrrolidine; 4-PP; PYR; 4-(Pyrrolidin-1-yl)pyridine; N-(Pyridin-4-yl)pyrrolidine
EINECS	219-513-2

Quality Control

Our 4-Pyrrolidinopyridine is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	84 - 88 °C
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.