Description

2-Trifluoromethylphenylmethylsulfone is a high-purity organosulfur compound featuring a trifluoromethylphenyl group, valued for its role as a versatile synthetic intermediate and building block. Its unique structure makes it a critical reagent for introducing specific functional groups in complex molecular architectures, particularly in advanced chemical synthesis. This product is essential for R&D and production within the pharmaceutical, agrochemical, and specialty chemical industries, where precise molecular construction is paramount.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring trifluoromethylated aromatic systems for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the sulfone and trifluoromethyl groups contribute to biological activity and environmental persistence.
• Material Science Research: Serves as a precursor for novel polymers, liquid crystals, and electronic materials that benefit from fluorine incorporation for thermal and chemical resistance.
• Organic Synthesis Reagent: Employed in cross-coupling reactions, nucleophilic substitutions, and as a scaffold for constructing complex heterocycles in academic and industrial research laboratories.
• Fluorine Chemistry Studies: An important compound for investigating the effects of fluorine substitution on reaction mechanisms and physical properties in medicinal and synthetic chemistry.

Basic Information

Product Name	2-Trifluoromethylphenylmethylsulfone
CAS No.	2443-77-8
Molecular Formula	C8H7F3O2S
Molecular Weight	224.20 g/mol
Synonyms	α,α,α-Trifluoro-o-tolyl Methyl Sulfone; (2-Trifluoromethylphenyl)methyl sulfone; 1-Methylsulfonyl-2-(trifluoromethyl)benzene; 2-(Trifluoromethyl)phenyl Methyl Sulfone; 2-(Methylsulfonyl)benzotrifluoride; o-Trifluoromethylphenyl Methyl Sulfone; Benzene, 1-methylsulfonyl-2-(trifluoromethyl)-; 2-Trifluoromethyl Phenyl Methyl Sulphone
EINECS	Contact for details

Quality Control

Our 2-Trifluoromethylphenylmethylsulfone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to confirm identity, potency, and impurity profiles. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.