Description

Tetrahydrofuran-2-Acetic Acid Ethyl Ester is a versatile heterocyclic ester compound that serves as a valuable building block in advanced organic synthesis. Its molecular structure, combining a tetrahydrofuran ring with an ester functional group, makes it a critical intermediate for creating complex molecules with specific stereochemistry and functionality. This compound is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and specialty chemical sectors for developing active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: Key starting material or chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides where its heterocyclic core contributes to biological activity.
• Fine Chemical Production: Serves as a precursor for flavors, fragrances, and other high-value specialty chemicals requiring specific ester functionalities.
• Polymer & Material Science: Acts as a monomer or modifying agent in the synthesis of specialized polymers, resins, and coatings.
• Academic & Industrial Research: Employed in methodological development and exploratory chemistry as a versatile scaffold for constructing complex molecular architectures.
• Ligand & Catalyst Development: Utilized in the preparation of chiral ligands and organocatalysts for asymmetric synthesis applications.

Basic Information

Product Name	Tetrahydrofuran-2-Acetic Acid Ethyl Ester
CAS No.	2434-02-8
Molecular Formula	C8H14O3
Molecular Weight	158.20 g/mol
Synonyms	Ethyl 2-(Tetrahydrofuran-2-yl)acetate; 2-(Tetrahydro-2-furanyl)acetic Acid Ethyl Ester; Ethyl (Tetrahydrofuran-2-yl)acetate; Tetrahydro-2-furanacetic Acid Ethyl Ester; Ethyl Tetrahydro-2-furylacetate; 2-(Oxolan-2-yl)acetic acid ethyl ester; THF-2-Acetic Acid Ethyl Ester; 2-Tetrahydrofuranylacetic Acid Ethyl Ester
EINECS	219-408-9

Quality Control

Our Tetrahydrofuran-2-Acetic Acid Ethyl Ester is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including chromatography (GC/HPLC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP and ISO 9001 standards for pharmaceutical and industrial applications, ensuring reliable supply for critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C/59-77°F). Keep away from heat, sparks, open flames, and incompatible materials such as strong acids, bases, and oxidizing agents. The container should be kept tightly sealed when not in use to prevent moisture absorption and maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Gravity (20°C)	1.040 - 1.060
Refractive Index (20°C)	1.430 - 1.440

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.