Description

4-Chloro-2-Hydroxybenzaldehyde is a versatile aromatic aldehyde derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both a formyl group and a phenolic hydroxyl group ortho to a chloro substituent, makes it a valuable building block for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those with benzofuran or benzopyran cores.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators, leveraging its halogenated phenolic structure.
• Ligand and Chelating Agent Precursor: Serves as a starting material for synthesizing Schiff base ligands used in catalysis and metal complexation.
• Dye and Pigment Manufacturing: Intermediate for creating specialized azo dyes and organic pigments due to its reactive aldehyde and hydroxyl groups.
• Organic Synthesis Building Block: Employed in heterocyclic chemistry for constructing compounds like benzoxazoles and coumarin derivatives.
• Research & Development: A valuable reagent in academic and industrial R&D for exploring new chemical entities and reaction pathways.

Basic Information

Product Name	4-Chloro-2-Hydroxybenzaldehyde
CAS No.	2420-26-0
Molecular Formula	C7H5ClO2
Molecular Weight	156.57 g/mol
Synonyms	2-Hydroxy-4-chlorobenzaldehyde; 4-Chlorosalicylaldehyde; 4-Chloro-2-formylphenol; 4-Chlorosalicylic aldehyde; 4-Chloro-2-hydroxybenzenecarboxaldehyde; 4-Chloro-2-hydroxy-benzaldehyde; 4-Chloro-salicylaldehyd
EINECS	219-350-4

Quality Control

Our 4-Chloro-2-Hydroxybenzaldehyde is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical parameters. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	118°C - 122°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.