Description

2-Phenyl-1,3,2-Dioxaborolane-4-Methanol is a versatile organoboron compound characterized by a cyclic boronic ester structure. This compound is a valuable synthetic intermediate, prized for its reactivity in cross-coupling reactions and as a protecting group for diols. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for the development of novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key building block in Suzuki-Miyaura cross-coupling reactions for synthesizing complex biaryl structures found in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides requiring boronic ester functionalities.
• Polymer Chemistry: Serves as a monomer or cross-linking agent in the development of specialty polymers and boron-containing materials.
• Diol Protection: Acts as a protecting group for 1,2- and 1,3-diols in multi-step organic synthesis, offering stability under various reaction conditions.
• Material Science Research: Investigated for use in the creation of organic light-emitting diodes (OLEDs) and other electronic materials.
• Chemical Synthesis Reagent: Employed in academic and industrial R&D laboratories for exploring new catalytic cycles and synthetic methodologies.

Basic Information

Product Name	2-Phenyl-1,3,2-Dioxaborolane-4-Methanol
CAS No.	2412-76-2
Molecular Formula	C9H11BO3
Molecular Weight	177.99 g/mol
Synonyms	4-(Hydroxymethyl)-2-phenyl-1,3,2-dioxaborolane; 2-Phenyl-4-hydroxymethyl-1,3,2-dioxaborolane; (4-Hydroxymethyl-2-phenyl-1,3,2-dioxaborolan); Phenylboronic acid 1,2-propanediol ester; 1,2-Propanediol cyclic phenylboronate; Phenylboronic acid cyclic ester with 1,2-propanediol; 2-Phenyl-1,3,2-dioxaborinane-4-methanol (related structure); PBDM
EINECS	Contact for details

Quality Control

Our 2-Phenyl-1,3,2-Dioxaborolane-4-Methanol is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 95.0% (by Titration)
Melting Point	Contact for details
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.