Description

2-Chloro-5-Methoxyaniline is a versatile aromatic amine intermediate characterized by its chloro and methoxy substituents, which impart unique reactivity. This compound is crucial for the synthesis of complex molecules, offering a balance of electronic properties for targeted chemical transformations. It is primarily sought after by manufacturers in the pharmaceutical, agrochemical, and dye industries for the development of active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds with specific receptor-binding profiles.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and pesticides, where its aniline core is functionalized to create potent bioactive molecules.
• Dye and Pigment Manufacturing: Serves as a precursor for azo dyes and other complex colorants, contributing to hue and fastness properties.
• Organic Synthesis: A valuable reagent for introducing the 2-chloro-5-methoxyphenyl moiety into more complex structures via coupling, condensation, or cyclization reactions.
• Research & Development: Employed in academic and industrial R&D labs for exploring new synthetic pathways and developing novel chemical entities.
• Polymer Chemistry: Can be utilized as a monomer or modifier in the synthesis of specialty polymers and resins.

Basic Information

Product Name	2-Chloro-5-Methoxyaniline
CAS No.	2401-24-3
Molecular Formula	C7H8ClNO
Molecular Weight	157.60 g/mol
Synonyms	5-Methoxy-2-chloroaniline; 2-Chloro-5-methoxybenzenamine; 2-Chloro-5-aminoanisole; 1-Amino-2-chloro-5-methoxybenzene; 2-Chloro-5-methoxyphenylamine; 5-Methoxy-o-chloroaniline; Aniline, 2-chloro-5-methoxy-; Benzenamine, 2-chloro-5-methoxy-
EINECS	219-287-5

Quality Control

Our 2-Chloro-5-Methoxyaniline is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Light yellow to brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	68°C - 72°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.